Kai Wu Selected Research

2019-nCoV Vaccine mRNA-1273

2/2022	Boosting with Omicron-matched or historical mRNA vaccines increases neutralizing antibody responses and protection against B.1.1.529 infection in mice.
1/2022	Boosting with variant-matched or historical mRNA vaccines protects against Omicron infection in mice.
12/2021	Variant SARS-CoV-2 mRNA vaccines confer broad neutralization as primary or booster series in mice.
10/2021	Variant SARS-CoV-2 mRNA vaccines confer broad neutralization as primary or booster series in mice.
10/2021	mRNA-1273 protects against SARS-CoV-2 beta infection in nonhuman primates.
8/2021	Protection against SARS-CoV-2 Beta Variant in mRNA-1273 Boosted Nonhuman Primates.
5/2021	Evaluation of mRNA-1273 against SARS-CoV-2 B.1.351 Infection in Nonhuman Primates.
4/2021	Immune Correlates of Protection by mRNA-1273 Immunization against SARS-CoV-2 Infection in Nonhuman Primates.
10/2020	SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness.

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Kai Wu Research Topics

Disease

62	Neoplasms (Cancer) 05/2022 - 07/2003
17	Neoplasm Metastasis (Metastasis) 01/2022 - 06/2011
14	Infections 02/2022 - 07/2003
12	Inflammation (Inflammations) 04/2022 - 10/2005
9	Esophageal Neoplasms (Esophageal Cancer) 12/2020 - 01/2014
9	Pancreatic Neoplasms (Pancreatic Cancer) 01/2020 - 07/2003
8	Esophageal Squamous Cell Carcinoma 05/2022 - 01/2014
8	Carcinogenesis 01/2022 - 01/2009
8	Stomach Neoplasms (Stomach Cancer) 01/2022 - 07/2010
8	Schizophrenia (Dementia Praecox) 10/2021 - 10/2017
8	Hypoxia (Hypoxemia) 01/2021 - 02/2016
7	Malaria 01/2022 - 01/2018
7	Acute Necrotizing Pancreatitis 01/2018 - 08/2002
7	Carcinoma (Carcinomatosis) 11/2017 - 09/2003
6	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 03/2022 - 08/2019
6	Lung Neoplasms (Lung Cancer) 01/2021 - 12/2013
5	COVID-19 12/2021 - 10/2020
5	Hyperthermia 09/2021 - 11/2014
4	Cognitive Dysfunction 01/2022 - 11/2010
4	Colorectal Neoplasms (Colorectal Cancer) 01/2022 - 06/2006
4	Melanoma (Melanoma, Malignant) 01/2021 - 01/2017
4	Asthma (Bronchial Asthma) 06/2015 - 10/2006
3	Spinal Cord Injuries (Spinal Cord Injury) 02/2022 - 02/2016
3	Bipolar Disorder (Manic Depressive Psychosis) 01/2022 - 12/2021
3	Major Depressive Disorder (Major Depressive Disorders) 01/2022 - 01/2021
3	Virus Diseases (Viral Diseases) 01/2022 - 06/2013
3	Osteosarcoma (Osteogenic Sarcoma) 01/2020 - 01/2016
3	Dehydration (Water Stress) 07/2019 - 02/2009
3	Hypertension (High Blood Pressure) 07/2019 - 03/2010
3	Lymphatic Metastasis 01/2019 - 08/2013
3	Gallbladder Neoplasms (Gallbladder Cancer) 07/2016 - 11/2005
3	Chronic Obstructive Pulmonary Disease (COPD) 06/2015 - 02/2011
2	Overweight 01/2022 - 11/2021
2	Pain (Aches) 01/2022 - 02/2020
2	Ulcerative Colitis 01/2022 - 03/2015
2	Adenocarcinoma of Lung 01/2022 - 08/2015
2	Urinary Bladder Neoplasms (Bladder Cancer) 01/2021 - 01/2021
2	Parkinson Disease (Parkinson's Disease) 12/2020 - 01/2016
2	Ischemia 01/2020 - 01/2017
2	Adenocarcinoma 01/2020 - 09/2011
2	Mental Disorders (Mental Disorder) 01/2020 - 07/2016
2	Heart Failure 01/2020 - 01/2017
2	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 10/2019 - 08/2019
2	Hepatocellular Carcinoma (Hepatoma) 03/2019 - 05/2016

Drug/Important Bio-Agent (IBA)

21	Proteins (Proteins, Gene)FDA Link 01/2022 - 08/2010
14	MicroRNAs (MicroRNA)IBA 01/2022 - 01/2014
14	Pharmaceutical PreparationsIBA 03/2021 - 10/2006
14	Biomarkers (Surrogate Marker)IBA 01/2021 - 10/2010
13	Long Noncoding RNAIBA 01/2022 - 08/2015
10	Messenger RNA (mRNA)IBA 01/2021 - 10/2005
9	2019-nCoV Vaccine mRNA-1273IBA 02/2022 - 10/2020
9	Biological ProductsIBA 01/2022 - 08/2010
8	Cisplatin (Platino)FDA LinkGeneric 01/2021 - 01/2014
7	DNA (Deoxyribonucleic Acid)IBA 04/2021 - 07/2003
7	Small Interfering RNA (siRNA)IBA 01/2020 - 10/2010
7	Atrial Natriuretic Factor (ANF)IBA 01/2018 - 08/2002
6	VaccinesIBA 02/2022 - 01/2020
5	AntigensIBA 01/2020 - 11/2015
4	Ketamine FDA LinkGeneric 01/2022 - 12/2021
4	Antidepressive Agents (Antidepressants)IBA 01/2022 - 01/2021
4	Antimalarials (Antimalarial Agents)IBA 01/2022 - 01/2018
3	Neutralizing AntibodiesIBA 02/2022 - 10/2020
3	CytokinesIBA 01/2022 - 01/2021
3	Therapeutic UsesIBA 01/2022 - 08/2004
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2022 - 10/2005
3	Contrast MediaIBA 03/2021 - 01/2017
3	Transcription Factors (Transcription Factor)IBA 03/2021 - 01/2009
3	Tyrosine Kinase InhibitorsIBA 08/2019 - 09/2008
3	ErbB Receptors (EGF Receptor)IBA 08/2019 - 09/2008
3	Complementary DNA (cDNA)IBA 02/2018 - 07/2010
3	Rosiglitazone (Avandia)FDA Link 07/2016 - 07/2003
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 05/2016 - 09/2008
3	PPAR gammaIBA 11/2010 - 07/2003
3	LigandsIBA 01/2010 - 07/2003
2	sintilimabIBA 03/2022 - 06/2021
2	HydrogelsIBA 02/2022 - 01/2021
2	mRNA VaccinesIBA 02/2022 - 01/2022
2	N-methyl-valyl-amiclenomycin (BA 2)IBA 01/2022 - 01/2022
2	Genetic Markers (Genetic Marker)IBA 01/2022 - 04/2019
2	Polysaccharides (Glycans)IBA 01/2022 - 01/2020
2	N-(2-cyanoethylene)urea (BA 1)IBA 01/2022 - 01/2022
2	NucleotidesIBA 01/2022 - 10/2011
2	anlotinibIBA 01/2022 - 06/2021
2	COVID-19 VaccinesIBA 12/2021 - 10/2021
2	CalciumIBA 11/2021 - 07/2019
2	HomocysteineIBA 10/2021 - 01/2020
2	CollagenIBA 01/2021 - 01/2021
2	Competitive Endogenous RNAIBA 01/2021 - 12/2016
2	MethyltransferasesIBA 01/2021 - 11/2018
2	Hypoxia-Inducible Factor 1IBA 08/2020 - 02/2016
2	Galactose (Galactopyranose)FDA LinkGeneric 01/2020 - 01/2015
2	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2020 - 07/2003
2	Gefitinib (Iressa)FDA Link 08/2019 - 12/2013
2	RNA (Ribonucleic Acid)IBA 01/2019 - 08/2015
2	CholesterolIBA 11/2018 - 03/2010

Therapy/Procedure

17	Therapeutics 05/2022 - 09/2008
9	Drug Therapy (Chemotherapy) 01/2022 - 05/2014
3	Immunotherapy 09/2021 - 02/2014
2	Microspheres (Microsphere) 05/2022 - 03/2021
2	Lasers (Laser) 05/2022 - 09/2021